李孟真
| 職稱 | 教授 |
| 研究室 | T2-947 |
| 分機 | 4408 |
| 信箱 | mjlee@cyut.edu.tw |
| 專長 | 中草藥藥效研究、脊椎損傷、蛋白質體學、奈米合成 |
學校經歷 |
| 學校 | 國別 | 系所 | 學位 | 起訖年月 |
| University College, London | 英國 | Neurobiology | Ph.D. | 1993 / 10 至1998 /11 |
| University College, London | 英國 | Neuroscience | M.Sc | 1992/ 10 至 1993/10 |
| 台灣大學 | 台灣 | 動物系動物生物組 | B.Sc | 1988 / 09 至1992 /06 |
工作經歷 |
| 服務機關 | 部門/系所 | 職稱 | 起迄年月 |
| 朝陽科技大學 | 應用化學系 | 教授 | 2022/08-訖今 |
| 朝陽科技大學 | 應用化學系 | 副教授 | 2010/02-2022/07 |
| 朝陽科技大學 | 生物技術所 | 助理教授 | 2004/08-2010/01 |
| 輔英科技大學 | 生物技術系 | 助理教授 | 2002/08-2004/07 |
| 微晶生技(股) | 研發部分子病理組 | 研究員 | 2000/09-2002/08 |
| 中央研究院 | 生物醫學研究所 | 博士後研究 | 1999 / 01至2000/ 07 |
期刊論文 |
| 年度 | 著作 |
| 2024 | Serang, Y., C. Chen and M. Lee (2024). "Green Synthesis of Magnesium Oxide Nanoparticles Using Melaleuca leucadendra Waste." Materials Science Forum 1123: 109-118. |
| 2024 | Serang, Y., C.-N. Chen and M.-J. Lee (2024). "Antioxidant dynamics in Cajanus cajan (L.) and Melaleuca leucadendra (L.): From plants to nanoparticles." BIO Web Conf. 125: 03002. |
| 2024 | Medidi Raja Sekhar, Nagaraj Basavegowda, Levin Anbu Gomez, Asma Musfra Shabbirahmed,Puneetha Gangadahosahalli Krishnegowda, Sivamani Sivalingam, Rajkumar Sekar, SanthoshKumar Jayakodi, Meng-Jen Lee*, and Prathap Somu* (2024) Visible-light driven photocatalytic degradation of organic dyes by carbonized palladium-impregnated graphene oxide quantum dots. Inorganic and Nano-metal Chemistry. https://doi.org/10.1080/24701556.2024.2356046 |
| 2023 | Li-Yu Fay, Chao-Hung Kuo, Hsuan-Kan Chang, Mei-Yin Yeh, Chih-Chang Chang ,Chin-Chu Ko, Tsung-Hsi Tu, Yi-Hsuan Kuo, Wang-Yu Hsu, Chien-Hui Hung,Ching-Jung Chen, Jau-Ching Wu, May-Jywan Tsai, Wen-Cheng Huang, Henrich Cheng and Meng-Jen Lee. Comparative Study of the Cytokine Profiles of Serum and Tissues from Patients with the Ossification of the Posterior Longitudinal Ligament. Biomedicines. 2023; 11(7):2021. https://doi.org/10.3390/biomedicines11072021 SJR 587 /2527, MEDICINE, micellaneous |
| 2023 | Rajendrachari, S., N. Basavegowda, R. Vinaykumar, D. Narsimhachary, P. Somu and M.-J. Lee (2023). "Electrocatalytic determination of methyl orange dye using mechanically alloyed novel metallic glass modified carbon paste electrode by cyclic voltammetry." Inorganic Chemistry Communications 155: 111010. 26/70 (Inorganic chemistry) |
| 2023 | Isaq, M., Y. L. Ramachandra, P. S. Rai, A. Chavan, R. Sekar, M.-J. Lee and P. Somu (2023). "Biogenic synthesized silver nanoparticles using fungal endophyte Cladosporium oxysporum of Vateria indica induce apoptosis in human colon cancer cell line via elevated intracellular ROS generation and cell cycle arrest." Journal of Molecular Liquids 386: 122601. 12/75 (Chemistry/spectroscopy) |
| 2022 | Sridharan B, Lee MJ. (2022) Ketogenic diet: A promising neuroprotective composition for managing Alzheimer's diseases and its pathological mechanisms. Curr Mol Med. 22(7) 640-656. 2022 Jan 6th. PMID: 34607541 (IF=2.616, MEDICINE, miscellaneous,1215/2574, Q2) |
| 2022 | Badrinathan Sridharan1, Shu-Yu Yang2, Jen-Ying Li2, Meng-Jen Lee1* (2022) Effect of Cynanchum paniculatum (Bge.) Kitag. on various diseases: an overview of current research progress. International Journal of Applied Science and Engineering. 19(1), p1-11. 2022 March. (SCOPOUS listed) (agriculture and biological science, miscellaneous 232/346, chemical engineering miscellaneous 242/414, engineering miscellaneous 349/648, control of optimization 340/898, numerical analysis 61/95, Q2) |
| 2022 | Badrinathan Sridharana, Yi-Lo Linb, Yi-Jyun Kunga, Meng-Jen Lee (2022) Andrographolide regulates phosphorylated p38 mitogen-activated .protein kinases and phosphorylated ERK expression in spinal cord and reduces postoperative pain in rats. Materials Today: Proceedings. Volume 57, Part 2, 2022, Pages 829-833, https://doi.org/10.1016/j.matpr.2022.02.438. (SCOPOUS listed) |
| 2022 | Badrinathan Sridharana, Jiann-Yeu Chenb, Siti Raudhatul Kamalia, Chang Nan Chena, Ting-Xuan Liua, Qing Luo-Fanga, Yi-Jyun Kunga, Meng-Jen Lee. (2022). Synthesis of magnesium-based microparticles using oil cake of Plukenetia volubilis (Inca fruit) seeds and study of its radical scavenging activity. Materials Today: Proceedings. Volume 57, Part 2, 2022, Pages 887-891. (SCOPOUS listed) https://doi.org/10.1016/j.matpr.2022.02.569 |
| 2022 | Lee, M. J., M. J. Tsai, W. C. Chang, W. Y. Hsu, C. H. Hung, Y. T. Chen, T. H. Tu, C. H. Shu, C. J. Chen and H. Cheng (2022). "Exogenous FGF-1 Differently Regulates Oligodendrocyte Replenishment in an SCI Repair Model and Cultured Cells." Biomedicines 10(11). 10.3390/biomedicines10112724 (SCI, IF=4.757, MEDICINE, micellaneous, 587/2527, Q1) |
| 2022 | Lin, Y.-L., J.-W. Liao, S. Wang, B. Sridharan, H.-J. Lee, A. Li, K.-M. Chang, C.-Y. Wu, S. Huang, K.-T. Chang, D. C. Agrawal, C.-J. Chen and M.-J. Lee (2022) "Andrographolide Relieves Post-Operative Wound Pain but Affects Local Angiogenesis." Pharmaceuticals 15 DOI: 10.3390/ph15121586. (SCI, IF=5.215, drug discovery, 35/159, Q1) |
| 2022 | Tsai, M.-J., L.-Y. Fay, D.-Y. Liou, Y. Chen, Y.-T. Chen, M.-J. Lee, T.-H. Tu, W.-C. Huang and H. Cheng (2023). "C." International Journal of Molecular Sciences 24(1): 421. 27 December 2022 (SCI, IF=6.201, BIOCHEMISTRY & MOLECULAR BIOLOGY, 69/297, Q1) |
| 2021 | Ku WC, Sridharan B, Chen JY, Li JY, Yang SY, Lee MJ*. Kaempferitrin-Treated HepG2 Differentially Expressed Exosomal Markers and Affect Extracellular Vesicle Sizes in the Secretome. Biomolecules. 2021 Jan 29;11(2):187. doi: 10.3390/biom11020187. PMID: 33572893. (impact factor=4.082, JCR biochemistry and molecular biology, 98/297, Q2) |
| 2021 | Badrinathan Sridharan, Meng-Jen Lee* (2021) Current developments in Nano/Micro-formulations for enhanced delivery and bioactivity of andrographolide, Materials Today: Proceedings 45 (2021) 4746–4752 https://doi.org/10.1016/j.matpr.2021.01.183. |
| 2021 | Shu-Yu Yang, Jen-Ying Li, Guan-Jhong Huang, Badrinathan Sridharan, Jen-Shu Wang, Kai-Ming Chang, Meng-Jen Lee* (2021) Effects of water extract of Cynanchum paniculatum (Bge.) Kitag. on different breast cancer cells lines. Evidence-Based Complementary and Alternative Medicine. Volume 2021, May 26, Article ID 6665949, 13 pages (impact factor=1.813, JCR integrative complementary medicine, Q2, 12/28) |
| 2021 | B Sridharan, J M Zhang, M J Lee* (2021) In vitro anti-oxidant property and reduction of hyperglycemia-induced oxidation by hydroalcoholic extract of Phyllanthus emblica in cultured mesangial cell lines. IOP Conference Series: Earth and Environmental Science. 858(1):012003 (SCOPOUS listed) |
| 2021 | Badrinathan Sridharan, Yi-Xuan Zhong, Yerra Koteswara Rao, Yao-Ming Zeng, Meng-Jen Lee* (2021) Antioxidant activities of underexplored Chinese medicinal plant parts and their effect against high glucose-induced modulation of fibronectin expression. IOP Conference Series: Earth and Environmental Science. 858 012006 (SCOPOUS listed) |
| 2021 | Badrinathan Sridharan, Yi-Lo Lin, Jiunn-Wang Liao, Shunching Wang, Meng-Jen Lee* (2021) Effect of andrographolide on the pathological events during the surgical open wound healing process. IOP Conference Series: Earth and Environmental Science. 858(1):012007 (2021/12/15). (SCOPOUS listed) |
| 2020 | M J Lee, B L Liu, H R Kuo and C A Chang (2020) Mutagenicity test of Streptomyces Species culture filtrate using mouse lymphoma cell. IOP Conference Series: Earth and Environmental Science 594: 012015 (SCOPOUS listed) |
| 2020 | M J Lee1, B L Liu, J H Yen, C A Chang1 (2020) New microbial origin compound capable of destruct T4 bacterial phage structure. IOP Conference Series: Earth and Environmental Science 594: 012014 (SCOPOUS listed) |
| 2018 | Wang Huang-Chi,Tsay Hsin-Sheng, Shih Hui-Nung, ChenYi-An, Chang Kai-Ming, Agrawal Dinesh Chandra, Huang Sien-Dong , Lin Yi-Lo*, Lee Meng-Jen* (2018) Andrographolide relieved pathological pain generated by spared nerve injury model in mice. Pharmaceutical Biology, Dec;56(1):124-131. doi: 10.1080/13880209.2018.1426614. (SCI, IF=1.916, plant science 71/212, Q2) |
| 2018 | Chuan-Wen Chiu, Wen-Hung Huang, Huai-Sheng Kuo, May-Jywan Tsai, Ching-Jung Chen, Meng-Jen Lee*, Henrich Cheng* (2018) Local inhibition of matrix metalloproteinases reduced M2 macrophage activity and impeded recovery in spinal cord transected rats after treatment with fibroblast growth factor-1 and nerve grafts. Neural Regeneration Research (SCI, IF=2.234). Aug;13(8):1447-1454. doi: 10.4103/1673-5374.235302. |
| 2017 | May-Jywan Tsai , Chi-Ting Huang, Yong-San Huang , Ching-Feng Weng, Song-Kun Shyue, Ming-Chao Huang, Dann-Ying Liou , Yan-Ru Lin , Chu-Hsun Cheng , Huai-Sheng Kuo , Yilo Lin, Meng-Jen Lee, Wen-Hung Huang, Wen-Cheng Huang and Henrich Cheng (2017) Improving the regenerative potential of olfactory ensheathing cells by overexpressing prostacyclin synthetase and its application in spinal cord repair. Journal of Biomed Sci, 24: 34.(SCI, IF=2.799, medicine research experimental 51/128, Q2) |
| 2017 | Wei-chi Ku, Yi-ling Chang, Sheng-fa Wu, Hui-nung Shih, Yew-min Tzeng, Hui-ru Kuo, Kai-ming Chang, Dinesh Chandra Agrawal, Bing-lan Liu, Chin-an Chang, Siendong Huang, and Meng-jen Lee* (2017) A comparative proteomic study of secretomes in kaempferitrin-treated CTX TNA2 astrocytic cells. Phytomedicine 36 (2017) 137–144 doi: 10.1016/j.phymed.2017.09.015. Epub 2017 Sep 28 (SCI, IF= 3.526, chemistry medicinal 12/60 Q1) |
| 2017 | Chen-Shin Hung, Shih-Fang Chiu, Yuan-Chen Chiu, Meng-Jen Lee, Shu-Yu Yang, and Ren-Shu Wang (2017) A case report of menopause with Skin Nodules. TJ TCM 20(2): 187-200. DOI: 10.6516/TJTCM.2017.20(2)187. |
| 2015 | Tzeng YM and Lee MJ* (2015) Neurotective properties of kavalactones. Neural Regeneration Research. Jun; 10(6): 875–877. (SCI, IF=0.234, cell biology, 182/185, Neuroscience 245/252 ) |
| 2015 | Cheng CH, Lin CT, Lee MJ, Tsai MJ, Huang WH, Huang MC, Lin YL, Chen CJ, Huang WC, Cheng H. (2015) Local Delivery of High-Dose Chondroitinase ABC in the Sub-Acute Stage Promotes Axonal Outgrowth and Functional Recovery after Complete Spinal Cord Transection. PLoS One. 2015 Sep 22;10(9):e0138705. doi: 10.1371/journal.pone.0138705. eCollection 2015.( 15/64, Q1, interdisciplinary science, cited 5) |
| 2014 | Rao YK, Shih HN, Lee YC, Cheng WT, Hung HC, Wang HC, Chen CJ, Tzeng YM, Lee MJ. (2014) Purification of kavalactones from Alpinia zerumbet and their protective actions against hydrogen peroxide-induced cytotoxicity in PC12 cells. Journal of Bioscience and Bioengineering 118 (2014), pp. 679-688 (SCI, IF=1.87, 93/165, BIOTECHNOLOGY & APPLIED MICROBIOLOGY, 42/123, FOOD SCIENCE & TECHNOLOGY) |
| 2012 | Yew-Min Tzeng, Yi-Ching Lee, Wen-Tai Cheng, Huang-chi Wang, Hui-Nung Shih, Yerra Koteswara Rao, and Meng-Jen Lee* (2012) Effects of andrographolide and 14-deoxy-11,12-didehydroandrographolide on cultured primary astrocytes and PC12 cells. Life sciences 2012 Feb 13;90(7-8):257-66. Epub 2011 Nov 29 (SCI, IF=2.527, 107/261 pharmacology, 47/112 medicine, research, experimental, cited 0) |
| 2012 | Lin YL, Tsai MJ, Lo MJ, Chang SE, Shih YH, Lee MJ, Kuo HS, Kuo WC, Huang WC, Cheng H, Huang MC*. (2012) Evaluation of the antiangiogenic effect of Kringle 1-5 in a rat glioma model. Neurosurgery. 2012 Feb;70(2):479-89; discussion 489-90. (SCI, IF=2.785, 70/192, CLINICAL NEUROLOGY, 34/199, SURGERY,cited 0) |
| 2012 | May-Jywan Tsai,Pei-Jou Ho, Yi-Lo Lin, Ming-Chao Huang, Meng-Jen Lee, Dann-Ying Liou, Wen-Cheng Huang, Yu-Show Fu, Henrich Cheng (2012) Microglia-conditioned medium promotes locomotor recovery and neuroprotection after rat spinal cord injury. Advances in Bioscience and Biotechnology, 3, 524-530 |
| 2011 | Lee MJ, Chen CJ, Huang WC, Huang MC, Chang WC, Kuo HS, Tsai MJ, Lin YL, Cheng H*. (2011) Regulation of chondroitin sulphate proteoglycan and reactive gliosis after spinal cord transection: effects of peripheral nerve graft and fibroblast growth factor 1. Neuropathol Appl Neurobiol. 2011 Oct;37(6):585-9 (SCI, IF=3.80, 34/192 CLINICAL NEUROLOGY, 13/79, pathology, 70/244 neuroscience, cited 1) |
| 2011 | Kuo HS, Tsai MJ, Huang MC, Chiu CW, Tsai CY, Lee MJ, Huang WC, Lin YL, Kuo WC, Cheng H*. (2011) Acid fibroblast growth factor and peripheral nerve grafts regulate Th2 cytokine expression, macrophage activation, polyamine synthesis, and neurotrophin expression in transected rat spinal cords. J Neurosci. 2011 Mar 16;31(11):4137-47. (SCI, IF=7.115, 19/244, Neurosicnece, cited 11) |
| 2011 | Lin YL, Kuo HS, Lo MJ, Tsai MJ, Lee MJ, Huang WC, Kuo WC, Shih YH, Cheng H, Huang MC* (2011) Treatment with nerve grafts and aFGF attenuates allodynia caused by cervical root transection injuries. Restor Neurol Neurosci. 2011 May 23. 2011;29(4):265-74 (SCI, IF=2.510, 135/244, NEUROSCIENCES, cited 0 ) . |
| 2011 | Huang WC, Kuo HS, Tsai MJ, Ma H, Chiu CW, Huang MC, Yang LH, Chang PT, Lin YL, Kuo WC, Lee MJ, Liu JC, Cheng H*. (2011) Adeno-associated virus-mediated human acidic fibroblast growth factor expression promotes functional recovery of spinal cord-contused rats. J Gene Med. 2011 May;13(5):283-289. doi: 10.1002/jgm.1568. (SCI, IF=2.483, 50/112, MEDICINE, RESEARCH & EXPERIMENTAL, 63/158, BIOTECHNOLOGY & APPLIED MICROBIOLOGY, 83/158, GENETICS & HEREDITY, cited 0) |
| 2010 | Meng-Jen Lee, Yerra Koteswara Rao, Keru Chen, Yi-Ching Lee, Yi-Shuan Chung, Yew-Min Tzeng* (2010) Andrographolide and 14-deoxy-11,12-didehydroandrographolide from Andrographis paniculata attenuate high glucose-induced fibrosis and apoptosis in murine renal mesangeal cell lines. Journal of Ethnopharmacology. J Ethnopharmacol. 2010 Nov 11;132(2):497-505. Epub 2010 Sep 9. (SCI, IF=3.014, SCI, IF=3.014, 4/22, INTEGRATIVE & COMPLEMENTARY MEDICINE, 31/190, plant science, 78/261, PHARMACOLOGY & PHARMACY, cited: 5) |
| 2010 | Tsai MJ, Chen YM, Weng CF, Liou DY, Yang HC, Chen CH, Liao RI, Kuo FS,Chiu CW, Kuo HS, Huang MC, Lin YL, Lee MJ, Kuo WC, Huang WC, Cheng H*. (2010) Enhanced expression of glycine N-methyltransferase by adenovirus-mediated gene transfer in CNS culture is neuroprotective. Ann N Y Acad Sci. 2010 Jun;1199:194-203. (SCI, IF=3.155, 6/56, MULTIDISCIPLINARY SCIENCES,cited2 ) |
| 2009 | Yew-Min Tzeng, Keru Chen, Yerra K Rao, and Meng-Jen Lee*. (2009) Kaempferitrin activates the insulin signaling pathway and stimulates secretion of adiponectin in 3T3-L1 adipocytes. Eur J Pharmacol 607(1-3):27-34. (SCI, IF=2.516 108/261 PHARMACOLOGY & PHARMACY, cited 13). (corresponding author) |
| 2009 | Lee MJ, Rao YK, Chen K, Lee YC, Tzeng YM* (2009) Effect of flavonol glycosides from Cinnamomum osmophloeum leaves on adiponectin secretion and phosphorylation of insulin receptor-beta in 3T3-L1 adipocytes. J Ethnopharmacol. 2009. Oct 29;126(1):79-85 (SCI, IF=3.014, 4/22, INTEGRATIVE & COMPLEMENTARY MEDICINE, 31/190, plant science, 78/261, PHARMACOLOGY & PHARMACY, cited 9) |
| 2009 | Yerra Koteswara Rao, Meng-Jen Lee, Keru Chen, Yi-Ching Lee, Yew-Min Tzeng* (2009) Insulin-mimetic Action of Rhoifolin and Cosmosiin Isolated from Citrus grandis (L.) Osbeck Leaves: Enhanced Adiponectin Secretion and Insulin Receptor Phosphorylation in 3T3-L1 Cells. Evidence Based Complementary and Alternative Medicine. Epub, Mar 10 2011 (SCI, IF=4.774, 1/22, INTEGRATIVE & COMPLEMENTARY MEDICINE, cited 1) |
| 2008 | Meng-Jen Lee, Ching Jung Chen, Chu-Hsun Cheng, Wen-Cheng Huang, Huai-Sheng Kuo, Jau-Ching Wue, May J. Tsai, Ming-Chao Huang, Wen-Chi Chang, Henrich Cheng (2008) Combined treatment using peripheral nerve graft and acidic FGF: Changes to the glial environment and differential macrophage reaction in a complete transected spinal cord. Neuroscience Letter, 433 (2008) 163–169 (SCI, IF=2.1, 170/244, neuroscience). (cited 7) |
| 2007 | Huang M.C., P.T. Chang, M.J. Tsai, H.S., Kuo H.S., W.C. Kuo, M.J. Lee, M. J. Lo, I.H. Lee, W.C. Huang, L.M. Lee, Y.H. Shih, L.S. Lee and H. Cheng (2007) Seonsory and motor recovery after repairing transected cervical roots. Surgical Neurology 2007;68 Suppl 1:S17-24; discussion S24. Epub 2007 Feb 15. (SCI). |
| 2007 | Huai-Sheng Kuo, May J Tsai, Ming-Chao Huang, Wen-Cheng Huang, Meng-Jen Lee, Wen-Chun Kuo, Li-Hua You, Ka-Chun Szeto, I-Lun Tsai, Wen-Chi Chang, Chuan-Wen Chiu, Hsu Ma, Kin-Fu Chak, Henrich Cheng*. The Combination of Peripheral Nerve Grafts and Acidic Fibroblast Growth Factor Enhances Arginase I and Polyamine Spermine Expression in Transected Rat Spinal Cords. Biochemical and Biophysical Research Communications, 2007 May 25;357(1):1-7. Epub 2007 Mar 28 (SCI). |
| 2001 | M.J. Lee., Calle, E., Brennan, A., Ahmed, S., Svidersakaya, E., Jessen, K. R. and Mirsky, R. (2001) In early Development of the Rat mRNA for the Major Myelin, Protein P0 is Expressed in sonsensory Areas of the Emrbyonic Inner Ear, Notochord, Enteric Nervous System, and Olfactory Ensheathing cells. Developmental Dynamics 222, 40-51. (SCI) |
| 2000 | Hu, H-M., Tseng, T-C., Chuang, C-K., Lee, M. J. and Tang, K. T. (2000) Genomic Organization, Expression, and Chromosome Localization of a Third Mouse Aurora-related kinase gene, AIE1. DNA and cell biology. 19(1), 679-688. (SCI) |
| 1997 | M.-J. Lee, A Brennan, A. Blanchard, G. Zoidl, Z. Dong, A. Tabernero, C. Zoidl, M.A.R.Dent, K.R.Jessen and R.Mirsky (1997) P0 is constitutively Expressed in the Rat Neural Crest and Embryonic Nerves and Is Negatively and Positively Regulated by Axons to Generate Non-Myelin-Forming and Myelin-Forming Schwann cells, Respectively. Mol. Cell. Neuroscience (8): 336-350. (SCI) |
研討會論文 |
| 年度 | 著作 |
| 2019 | Meng-Jen Lee, Kai-Ting Chang, Siendong Huang, Yilo Lin (2019) Andrographolide relieved pain generated by post-operative pain model in rat for short as well as longer time frame. 9th Federation of the Asian and Oceanian physiological societies Congress. 亞洲和大洋洲生理學會聯合大會, 神戶 日本 2019/03/28-/03/31. |
| 2018 | Meng-Jen Lee, Huei-Ru Kuo, Bing-Lan Liu, Ching-An Chang (2018) Effect of new microbial origin compound on virus to orchid infectivity and T4 bacterial phage to E Coli infectivity. 第三十三屆生物醫學聯合年會。台北 2018/03/24-25. |
| 2018 | Wei-chi Kua, Sheng-fa Wub, Hui-nung Shihb, Yew-ming Tzengb,c, Hui-ru Kuob, Kai-ming Changd, and Meng-jen Lee*b (2018) A comparative proteomic study of secretomes in kaempferitrin-treated CTX TNA2 astrocytic cells. 18th World Congress of Basic and Clinical Pharmacology (WCP). Kyoto, Japan. 2018/07/01-7/06 |
| 2018 | Shun-Ching Wang, 1 *Hsin-Ju Li, 2Yi-Lo Lin, 1Meng-Jen Lee (2018) Evaluation of anti-pain sensation for ABL007 administered via different routes. 第十五屆實驗動物學會CSLAS 會員大會 台北 2018/11/15-11/16. |
| 2018 | Meng-Jen Lee, Huei-Ru Kuo, Bing-Lan Liu, Chin-An Chang (2018) Culture filtrate of streptomyces spp is capable of destructing the capsid structure Cymbidium mosaic virus. Abstract of 2018 Annual Meeting of The Plant Protection Society of Republic of China. Journal of Plant medicine Vol. 61 No. 2&3 (2019 / 09 / 01) ， P59 - 81 DOI： 10.6716/JPM.201909_61(2_3).0006 台灣 台中 2018/11/30 . |
| 2017 | Wei-chi Ku, Hui-Nung Shih, Yi-Ling Chang, Sheng-Fa Wu, and Meng-Jen Lee* (2017) A comparative proteomic study of secretomes in ABL007-treated CTX TNA2 astrocytic cells. 第三十二屆生物醫學聯合學術年會 台北 (2017/03/25-2017/03/26) |
| 2017 | S.V. Ganesan, B.L. Liu,, M.J. Lee,, C.A. Chang (2017) Biochemical characteriztion of serine protease-like enzyme-like from streptomyces alurentII . 7th Congress of European Microbiologists (FEMS), Valencia, Spain, 9-13 July 2017. |
| 2017 | Meng-Jen Lee, Huei-Ru Kuo, Bing-Lan Liu, Ching-An Chang (2017) New microbial origin compound capable of reduce virus to orchid infectivity and T4 bacterial phage to E Coli infectivity. International union of microbiologist society annual meeting, IUMS 2017 Singapore. 2017/07/17/2017/07/21. |
| 2016 | Sheng-Fa Wu, Yaw Nan Chang, Meng-Jen Lee (2016) The neuroprotective effect of herbal derived single compounds 第三十一屆生物醫學聯合學術年會 台北 (2016/03/26-2016/03/27) |
| 2015 | Meng-Jen Lee, Ching rong Chen, Wen-chi Chang, and Henrich Cheng (2015) A study of the inflammatory reaction in the nerve graft in a CNS repair model. Biomaterials international 2015, Kenting, Taiwan (2015/06/01-2015/06/05) |
| 2015 | Meng-Jen Lee ab, Ching Jung Chenb, Wen-Chi Changb, Henrich Chengbc(2015) Exogenous FGF-1 hault differentiation of NKX2.2+pre- OPC to NG2+ OPC in a rat spinal cord transection model. XII European Meeting on Glial Cells in Health and Disease. Bilbao, Spain (2015/07/14-2015/07/18). |
| 2014 | Huang-chi Wang1, Hui-Nung Shih1, Yi-An Chen1, Huang-chi Wang1, Yi-Lo Lin2, Meng-Jen Lee1* (2014) Allodynia Reduction Ability for a Single Compound ABL-006. 第二十九屆生物醫學聯合學術年會 台北 (2014/03/15- 2014/03/16) |
| 2014 | Yi-Ju Lu1, Meng-Jen Lee2* (2014) The Action of ABL-007 on PC12 Cells. 生物技術暨生物工程研討會. 台中 東海大學 (2014/03/03) |
| 2014 | Meng-Jen Lee1 ,Yilo Lin2, Huang-chi Wang1, Hui-Nung Shih1 (2014) A single compound ABL-006 reduced allodynia in a mouse sciatic nerve transection model. 9th Forum of Neuroscience, Federation of European Neuroscience Society, Milan, Italy (2014/07/05-2014/07/09) |
| 2013 | Yi-Lo Lin, Huang-chi Wang, Hui-Nung Shih, Yi-An Chen, Hsin-Sheng Tsay, Meng-Jen Lee* (2013) Allodynia reduction ability for a single compound ABL-006. 第二十八屆生物醫學聯合學術年會 台北 (2013/03/23- 2013/03/24) |
| 2013 | Yilo Lin, Huang-chi Wang, Hui-Nung Shih, Meng-Jen Lee (2013) ABL-006 reduced allodynia and central inflammation in sciatic nerve transected mice. 2013生命科學的跨領域整合與應用研討會台北 (2013/07/13- 2013/07/14) |
| 2012 | Yilo Lin, Huang-chi Wang, Hui-Nung Shih, Meng-Jen Lee* (2012) Allodynia reduction ability for a single compound ABL-006. 6th European Congress of Pharmacology. Granada, Spain. 2012/07/17-2012/07/20 |
| 2012 | Meng-Jen Lee, Yerra Koteswara Rao, and Yew-Min Tzeng* (2012) Preparation and bioassay of antioxidant neuroprotective constituents from Alpinia zerumbet. 15th International Biotechnology Symposium and Exhibition (IBS 2012), Daegu, Korea (2012/09/16- 2012/09/21) |
| 2011 | Cheng-H, Lee, MJ, Chen, C Chang, W. –C. (2011) Effects of combined treatment of fibroblastic growth factor (FGF)-1 and peripheral nerve (PN) graft ondemyelination, oligodendrocytes phenotype, and axon degeneration after spinal cord injury. Annual meeting for Society for Neuroscience, USA, Washington D.C.. 2011/11/12/-2010/11/16. |
| 2011 | Yi-ching Lee, YK Rao, YM Tzeng, Meng-Jen Lee* (2011) Modulation of TNF-α Mediated Inflammatory Response in Astrocytes by Chinese Herb Extract. 生命科學跨領域整合與應用國際研討會台灣宜蘭 2011/8/5 2011/8/6 |
| 2011 | Keru Chen*, Yerra Koteswara Rao, Yew-Min Tzeng, Meng-Jen Lee# (2011) The Insulinomimetic Activity of One Compound Isolated from Cinnamomum osmophloeum. 生命科學跨領域整合與應用國際研討會 台灣宜蘭 2011/8/5 2011/8/6 |
| 2010 | Yi-ching Lee, YK Rao, YM Tzeng, Meng-Jen Lee*(2010) Modulation of Akt, JNK, and p38 Activation Is Involved in Diterpene lactones-Mediated Cytoprotection of PC12 Cells Challenged by Hydrogen Peroxide. 第二十五屆生物醫學聯合學術年會 |
| 2010 | Wen-Tai Cheng, Hui-Chin Hung, Yew-Min Tzeng, Meng-Jen Lee* (2010) Neuroprotective Effects of DDK from Alpinia Speciosa Shell Against H2O2-Induced Cytotoxicity in PC12 Cells. 第二十五屆生物醫學聯合學術年會. |
| 2010 | Yi Wang, Yerra Koteswara Rao , Yew-Min Tzeng, Meng-Jen Lee*(2010) A single compound extracted from Antrodia camphorata increase Akt tyrosine phosphorylation in insulin resistant 3T3-L1 cells. 第二十五屆生物醫學聯合學術年會 |
| 2010 | Yew-Min Tzeng, Meng-Jen Lee, Hsiao-Sung Chan, Yerra Koteswara Rao, Wei-Chien Huang (2010) Isolation, capillary electrophoresis quantification and evaluation of preliminary molecular basis for insulin-like effects of flavonol glycosides from Cinnamomum osmophloeum leaves. 2010 International Symposium on Advanced Biological Engineering, Beijing. |
| 2010 | Yew-Min Tzeng, Yi-Ching Lee, Wen-Tai Cheng, Yerra Koteswara Rao, and Meng-Jen Lee*# (2010) Effects of androgrpaholide and 14-deoxy-11,12-didehydroandrographolide on cultured primary astrocytes and PC12 cells. 10th international conference on neuroprotective agents, Asimolar, California, USA. |
| 2010 | Meng-Jen Lee, Ching Rong Chen, Wen-Chi Chang, Henrich Cheng (2010) Effects of combined treatment of FGF-1 and PNS graft on demyelination, oligodendrocytes phenotype, and axon degeneration after spinal cord injury. Annual meeting for Society for Neuroscience, USA, San Diego. 2010/11/13-2010/11/17. |
| 2009 | Yi-ching Lee, YK Rao, YM Tzeng, Meng-Jen Lee (2009) Modulation of TNF-α Mediated Inflammatory Response in Astrocytes by Chinese Herb Extract. 第二十四屆生物醫學聯合學術年會 |
| 2008 | Keru Chen, Meng-Jen Lee, Yao-ming Tzeng (2008) Insulinomimetic activity of a single compound isolated from Cinnamomum osmophloeum leaves. 二十二屆生醫年會, 台灣，中華民國臺北. |
| 2008 | Meng-Jen Lee, Ching-Jung Chen, Wen-Chi Chang, Henrich Cheng (2008) Combinatorial treatment using peripheral nerve graft and aFGF reduce chondroitin sulphate proteoglycan deposition in the scar . 第二十三屆生物醫學聯合學術年會 |
| 2008 | Keru Chen, Meng-Jen Lee, Yew-Min Tzeng (2008) Insulinomimetic activity of kaempferitrin from leaves of Cinnamomum osmophloeum. Conference Abstract , 91st Canadian Chemistry Conference and Exhibition.. |
| 2008 | Meng-Jen Lee, Ching-Jung Chen, Wen-Chi Chang, Henrich Cheng (2008) CSPG deposition and grey matter preservation in rats received PNS graft and FGF-1 combined treatments after spinal cord transaction. Annual meeting for Society for Neuroscience, USA, Washington DC. 2008/10/15-2007/11/19 |
| 2008 | Yi-ching Lee, Wen-tai Cheng, YK Rao, YM Tzeng, Meng-Jen Lee (2008) Studies on neuroprotective effect of antioxidant Chinese herb extract. Conference Abstract, 4th ISBB conference, Taipei. |
| 2007 | H. KUO, M. Lee, M. J. TSAI, P. T. CHANG, W. C. HUANG, M. C. HUANG, J. R. CHEN, L. H. YOU, I. L. TSAI, W. C. CHANG, C. W. CHIU, H. CHENG. (2006) The combination of intercostal nerve graft with aFGF treatment induces the expression of MMP-2 and MMP-9 in T8-transected spinal cords.第二十一屆生醫年會, 台灣，中華民國 臺北. 2007/3/18-2007/3/19. |
| 2007 | Chu- Hsun Cheng, Henrich Cheng , Ching-Jung Chen, Hsiao-Ching Wei, Meng-Jen Lee (2007)脊髓修復模型中植入週邊肋間神經之神經崩解及再生之比較研究台灣幹細胞學會2007研討會, 台灣, 2007/4/14 |
| 2007 | Ching-Jung Chen , Chu- Hsun Cheng, Henrich Cheng, , Hsiao-Ching Wei, Meng-Jen Lee (2007) Repair operation reduces cavity size in the back-degenerative white matter. 台灣幹細胞學會2007研討會, 台灣. 2007/4/14. |
| 2007 | 12. Meng-Jen Lee (2007) Study of the mechanism of a CNS regeneration model. 口頭報告. 台灣幹細胞學會2007研討會, 台灣. 2007/4/14 |
| 2007 | Keru Chen, Meng-Jen Lee, Yao-ming Tzeng (2007) Preliminary study on the insulinomimetic activity of kaempferol glycosides isolated from Cinnamomum osmophloeum. APBioChEC, 台灣. 2007 Nov. |
| 2007 | 14. 14. Meng-Jen Lee, Ching-Jung Chen, Wen-Chi Chang, Henrich Cheng (2007) A combinatorial treatment using peripheral nerve graft and aFGF reduce chondroitin sulphate proteoglycan deposition in the scar. Annual meeting for Society for Neuroscience USA San Diego. 2007/11/03-2007/11/07 |
| 2006 | Yi-Hsuan Chung, Yerra Koteswara Rao, Ke-Ru Chen, Yew-Min Tzeng, Meng-Jen Lee (2006) Comparative studies analysis for antioxidant activities among several Chinese herbal extract. 生物醫學聯合年會. (06/03/18) |
| 2006 | Chu-Hsun Cheng, Ching-Jung Chen, Hsiao-Ching Wei, Wen-Chi Chang, Yang-Hsin Shih, Liang-Shong Lee, Henrich Cheng, Meng-Jen Lee (2006) Wallerian Degeneration and preservation of endoneurium of the PNS nerve graft in a CNS repair model生物醫學聯合年會. (06/03/18) |
| 2006 | Keru Chen, Meng-Jen Lee, Yerra Koteswara Rao, Yew-Min Tzeng٭ (2006) 台灣土肉桂葉中類黃酮糖苷的萃取與降血糖作用之研究. 第十一屆生化工程研討會與生醫奈米暨組織工程國際研討會, 台灣新竹市.2006/6/23-2006/6/24 |
| 2006 | Meng-Jen Lee, Ching-Jung Chen, Hsiao-Ching Wei, Wen-Chi Chang, Yang-Hsin Shih, Liang-Shong Lee, Henrich Cheng (2006) Down-regulation of glial scarring, progressive cavitation, and inhibitory proteoglycan, in a complete transected spinal cord by combinatorial repair strategy. Annual meeting for Society for Neuroscience USA Georgia, Atlanta. 2006/10/14-2006/10/18 |
| 2006 | Keru Chen, Meng-Jen Lee, Yerra Koteswara Rao, Yew-Min Tzen (2006) Preliminary study on the insulinomimetic activity of kaempferol glycosides isolated from a Taiwan endemic plant Cinnamomum osmophloeum. Symposium of Young Asia biochemical engineeer's community. Taiwan, Kaohsiung. 2006/11/25-2006/11/27. |
| 2005 | 李孟真,陳靜蓉,張文姬,鄭宏志 (2005) Down-regulated KSPG expression in the proximal stump and scar-cord interface after spinal repair. 生物醫學聯合年會. |
| 2005 | Meng-Jen Lee, Ching Rong Cheng, Hsiao-jing Wei, Wen Chi Chang, Herich HC Cheng (2005) An emergent structure of the nerve graft in a CNS repair model. 9th International Conference on Neural Transplantation and Repair, June 8-11, 2005, Taipei. |
| 2005 | Meng-Jen Lee, Ching-Jung Chen, Hsiao-Ching Wei, Wen-Chi Chang, Yang-Hsin Shih, Liang-Shong Lee, Henrich Cheng (2005) Wallerian Degeneration and preservation of endoneurium of the PNS nerve graft in a CNS repair model. Abstract Viewer/Itinerary Planner. Washington, DC: Society for Neuroscience, 2005. Online. |
專書及專書論文 |
| 年度 | 著作 |
| 2021 | Badrinathan Sridharan and Meng-Jen Lee* (2021) Andrographolide, a Diterpene from Andrographis paniculata, and its Influence on the Progression of Neurodegenerative Disorders. In: Agrawal DC and Dhanasekaran M (eds), Medicinal Herbs and Fungi – Neurotoxicity Vs Neuroprotection, Pages 79-1125. Publisher Springer Nature 2020 sep. |
| 2012 | Tsai MJ, SK Shyue, DY Liou, TH Yang, CF Weng, MC Huang, YL Lin, HS Kuo, MJ Lee, SL Huang, WC Huang, B J.Hoffer H Cheng (2012) Protective Effect of BMP-7 Overexpression via Adenovirus-Mediated Transfer on Spinal Cord Injury in Culture and in vivo. in “Handbook on Oxidative Stress: New Research”, edited by: Adolfo M. Reyes and Cristóbal D. Contreras. (Pub. Date: 2012 september), Chapter 15; pp415-430. publisher: Novapublisher ISBN: ISBN-10: 161942178X ISBN-13: 978-1619421783. |
| 1999 | M.-J. Lee. (1999) The Expression of P0 Gene During Development of Rat: basal level and its regulation . PhD Thesis. University of London. |
產學研究計畫 |
| 年度 | 計畫名稱 | 擔任工作 | 計畫時間 | 補助/委託機構 |
| 2023 | 融合差異化教學及BOPPPS教學設計之混合式教學: 雲端教學系統及行動裝置即時反饋之應用 | 主持人 | 2023年08月 ~ 2024年07月 | 教育部 |
| 2023 | 利用印加果油粕萃取物行金屬氧化物奈米化加工及產業之應用 | 主持人 | 2023年08月 ~ 2024年07月 | 國科會 |
| 2023 | 以奈米綠色科技加工田間廢棄物開發產品原料精進師生實務職能方案 | 主持人 | 2023年08月 ~ 2024年07月 | 教育部 |
| 2022 | 以生物化學工藝提升食品補充劑價值精進師生實務職能方案 | 主持人 | 2022年08月 ~ 2023年07月 | 教育部 |
| 2021 | 穿心蓮內酯緩解手術後傷口疼痛及與嗎啡共同使用之研究 | 主持人 | 2021年08月 ~ 2022年07月 | 科技部 |
| 2021 | 印加果油粕萃取檢測及產品開發計畫精進師生實務職能方案 | 主持人 | 2021年08月 ~ 2022年07月 | 教育部 |
| 2021 | 應用「混合式學習模式」及「合作學習」之科技英文課程改善計畫 | 主持人 | 2021年08月 ~ 2022年07月 | 教育部 |
| 2020 | 以「動手做」及「模擬開發英文STEM課程」為PBL的科技英文課程內容改善計畫 | 主持人 | 2020年08月 ~ 2021年07月 | 教育部 |
| 2020 | 餘甘子水酒萃物抗氧化及保護高糖引起之腎絲球毒性測試計畫 | 主持人 | 2020年08月 ~ 2021年07月 | 優杏生技 |
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